niFFERENTIAL DIAGNOSIS 425 



The spleen and lymphatic glands are enlarged. The liver 

 is enlarged and congested. The heart muscle is soft and 

 flabby. The lungs often contain ecchymoses and subpleural 

 emphysematous areas. There is a serofibrinous exudate in the 

 body cavities, especially in the pericardial sac and pleural 

 spaces. There are conflicting statements concerning the mor- 

 bid anatomy and it is difficult to select those that are not con- 

 tradicted. The pathological histology and the lesions in the 

 nervous system do not appear to have been described. 



§ 332. Differential diagnosis. This affection is to be 

 differentiated from the other forms of trypanosoma infections. 

 There seems to be no other specific disease with which it 

 would be confused. The diagnosis is made from the intermit- 

 tent fever, emaciation, progressive paresis, anemia, and the 

 finding of a parasite. The inoculation of experimental ani- 

 mals (mice or dogs) with the blood is of value when the 

 parasite is not found on microscopic examination in the blood 

 of the horse. 



REFERENCES. 



1. Elmassiax. Mai de Caderas. Anales de la Universidad 

 Nacioiial Asuncion, Vol. V (1901). 



2. Leclerc. El mal de Cadeias. Buefios Ayres, 1899. 



3. LiGNlERES. Contribuci6n al estudio de la trypanisomiasis de 

 los Equideos Sud Americanos. Buletin de agricultura y yanaderia 

 [Republic Argentina) 1902, p. 843. 



4. Rebourgeon. Note sur le mal de Cadera. Reineil de ml'd. 

 vHcr. 1889, p. 85. 



5. SivORi AND L,ECi<ER. Le Surra Amdricain ou mal de Caderas. 

 Anales del ministerio de agricultura, 1902. Centralbl. fi'ir allg. Path. 

 1902, S. 963. 



6. VoGES. Das mal de Caderas. Zeitschrift f. Hygiene, Bd. 

 XXXIX (1902), p. 323. 



See also literature on other trypanosoma. 



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