28o MANUAL OF BACTERIOLOGY. 



There are various species of each of them. They consist of 

 cells arranged end to end, making a thread-like body called a 

 hypha. The threads are matted together and form a mycelium. 

 Certain threads project upward from the mycelium, and on 

 them are borne spores. The arrangement of the spores is 

 characteristic in each variety of mould (Fig. 63). A group of 

 organisms exist which have affinities both with yeasts and 

 mould-fungi. Some of them are pathogenic. The form of 

 infection of the mouth called thrush is due to a fungus of this 

 class, which is generally considered an oidium. A chronic in- 

 flammatory affection of the skin (blastomycetic drematitis) is 

 due to related organisms.* Irons and Grahamf have reported 

 a case of generalized blastomycosis inwhich they isolated from 

 the several lesions during life and post-mortem an organism 

 corresponding with oidium as described by Ricketts. Others 

 have reported similar cases, but with more or less reserve as 

 to the etiological significance of the organism. Irons and 

 Graham excluded the tubercle bacillus, and furthermore ob- 

 tained positive results on the inoculation of animals, and they 

 regard the organism as the cause of the disease in the case 

 reported. 



LeCount and MeyersJ report a case of systemic blastomy- 

 cosis in which there were foci of infection very generally distrib- 

 uted throughout the body, involving not only the abdominal 

 and thoracic viscera, but also the cerebellum, and the left el- 

 bow and both knee and ankle-joints. 



Hamburger§ made a study of the organisms derived from four 

 cases reported respectively by ||Bassoe, Irons and Graham, T[ 



*Ricketts. Journal of Medical Research. Vol. VI., 1901. Hyde and 

 Montgomery. Journal American Medical Association. June 7, 1902. Ophiils. 

 Journ. Exper. Med. VI. 



■fjour. Infectious Diseases. Vol. III., pp. 443-682. 1906. 



JLeCount and Meyers. Journ. Inf. Dis. Vol. IV., 1907. pp. 187-200. 



^Journ. Infec. Dis. Vol. IV., r907. pp. 201-209. 



II Journ. Infect. Dis. 1906. p. gr. 



^ Loc. cit. supra. 



