PATHOGENIC BACTERIA. 299 



valent" streptococcus serum by using streptococci from various 

 sources for the injection of animals. The blood-serum of the 

 injected animals constitute the poUyvalent serum. It is im- 

 possible at present to speak definitely in regard to the value of 

 antistreptococcus serum since some seem to have obtained very 

 favorable results with it in practice, while others report no 

 observable improvement in cases treated with it. Since the 

 ■streptococci belong to that class of bacteria which form endo- 



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^-: :^im* . m 



V 



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IB 



Fig. 70.— Micrococcus tetragenus in pus from a large abscess on the arm, 

 showing capsule. Gram's stain and eosin. (X 1000.) 



toxins, the problem of producing an antitoxin is an unsatisfac- 

 tory matter, to say the least. 



It is said that streptococci may be agglutinated by serum 

 from animals immunized with streptococcus. 



Coley* recommends the use of mixed culture of Streptococ- 

 cus pyogenes (or S. erysipelatos) and B. prodigiosus in the 

 treatment of inoperable sarcomata. The cultures with which 

 he was very successful in a number of cases were prepared for 



♦Reprint from Med. Record. July 27, 1907. 



