380 ACUTE EXANTHEMATOUS INFECTIOUS DISEASES 



horns (very rare), nasal mucous membrane, conjunctiva, 

 pharynx (dysphagia, cough, regurgitation) and even the 

 cornea are similarly involved. 



The foot lesions induce lameness with knuckling of the 

 fetlock of the limb attacked. If two or more feet are affected 

 the patient lies down most of the time and is made to arise 

 with difficulty. The coronet is hot and swollen, especially 

 in front and between the bulbs of the heels. In some 

 cases the swelling extends up the leg to the middle of the 

 canon. On the second to third day of the attack pea- to 

 bean-sized vesicles appear in the swollen area. The vesicles 

 rupture very early and leave behind sores covered with a 

 tough, brown scab. Healing usually requires one to two 

 weeks. In severe cases, from secondary infection, shedding 

 of the claws results. 



In swine and sheep only the feet may be attacked, no 

 mouth lesions being apparent. 



In cows the skin of the teats and udder is frequently affected, 

 most often the former. The vesicles are from the size of a 

 pea to a hazel nut and are generally ruptured during milking. 

 The teats are swollen, sometimes phlegmonous (secondary 

 infection) and extremely sensitive. Later the sores become 

 covered with scabs and heal. 



Catarrhal mastitis frequently attends the exanthema lead- 

 ing to changes in the milk, which becomes colostral, has an 

 acid reaction, coagulates readily and is difficult to make into 

 butter or cheese. 



Complications and Sequels. — ^The most serious complica- 

 tions are phlegmons of the digits which lead to suppm-ative 

 inflammation of the tendon sheaths, tendons, joints and 

 ' hora matrix inducing severe general disturbance (fever, high 

 pulse), inability to stand, decubital gangrene, septicemia and 

 death in one to two weeks. 



Septic infection of, the udder (parenchymatous mastitis) 

 is not an uncommon complication which may cause the loss of 

 a quarter or a half of the organ. 



Gastro-enteritis is a fatal complication in calves leading to 

 death in two to three days. 



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