620 



PATHOGENIC MICROORGANISMS 



earliest observations were made upon microorganisms isolated from the 

 human conjunctiva. Nocard ' in 1888 described a member of this 

 group as the etiological factor in a disease "farcies du boeuf " occurring 

 among cattle in Guadeloupe. Eppinger ^ found streptothrices in the pus 

 of a cerebral abscess. Petruschky,^ Berestneff,* Flexner,' Norris and 



h'la 139. — Cladothrix. Showinq False Branching. 



Larking and a number of other observers have found these microor- 

 ganisms in cases of pulmonary disease, simulating tuberculosis. Sup- 

 purations of bone and of the skin and the intestinal canal have been 

 reported. The infection, therefore, is not very rare, but the diverse 

 experiences of workers who have attempted to cultivate these micro- 



' Nocard, Ann. de I'inst. Pasteur, ii, 1888. 



2 Eppinger, Wien. klin. Wooh., 1890. 



3 Petruschky, Verhandl. d. Kongr. f. innere Mediz., 1898. 

 « Berestneff, Zeit. f. Hyg., xxix, 1898. 



• Flexner, Jour. Exp. Med., iii, 1896. 



' Norris and Larkin, Proc. of N. Y. Path. Soc, March, 1899. 



