SWINE PLAGUE—DIAGNOSIS 57 
The acute bacteriemia form in which the lesions are characterized 
by a general hyperemic condition of the serous membranes and 
parenchymatous organs. Not infrequently hemorrhages, especially 
the punctiform variety, occur. No localized lesions. 
Cases of pneumonia with or without pleuritis. The other organs 
remain normal in appearance. 
Cases where either in addition to, or possibly in the absence of, the 
lung lesions there are marked anatomical changes in the mucosa of 
the digestive tract and possibly in the lymphatic glands. 
Cases of mixed infection, especially with hog cholera, where in 
addition to the swine-plague lesions which may be more or less 
modified, there are those, especially of the digestive tract, characteris- 
tic of the accompanying disease. 
The course of the disease varies in acute cases from one to three 
weeks. In chronic or complicated cases it is indefinite. 
The prognosis in swine plague is very unfavorable. Most of the 
affected animals die, and those that recover are usually not thrifty. 
Diagnosis. Swine plague is diagnosed from the symptoms, lesions 
and the bacteriological examination. There are no specific reactions 
that have been found to be satisfactory in making a diagnosis. 
Swine plague is to be differentiated from broncho-pneumonia due to 
other causes than the swine-plague bacterium. Pneumonia of a non- 
specific nature is often associated with deaths due to dietary or other 
causes. Pneumonia frequently produces death in chronic cases of 
other diseases (terminal pneumonia). 
In enzodtics or outbreaks, it is to be distinguished from hog cholera 
accompanied with catarrhal pneumonia. 
Pneumonia resulting from lung worms (Strongylus paradoxus) is to 
be distinguished by a careful examination of the contents of the 
bronchioles. 
In case of coexistence of hog cholera and swine plague a bacteriolo- 
gical examination and also the inoculation of pigs with the filtered 
blood serums, are necessary to determine the presence of the two 
diseases, owing to the possibility of an accompanying or terminal 
pneumonia with hog cholera. 
The question has arisen as to whether the presence of Bact. suisepti- 
cum in the hepatized lung constitutes a diagnosis of swine plague. 
As understood at the present time it would seem that the presence of 
this species of bacteria would indicate the nature of the disease. It 
