80 FOWL TYPHOID 
In these the portion of the cell body surrounding the nucleus remains 
unstained or becomes slightly tinted with blue. 
Occasionally they 
contain one or more vacuoles, and the margin is frequently broken. 
The apparent dissolving away of the red corpuscles has been fre- 
= 
Fic. 8. Bioop rRoM A WELL ADVANCED 
CASE OF FOWL TYPHOID SHOWING RED 
CORPUSCLES, BLOOD PLATES AND IN- 
CREASE IN THE NUMBER OF LEUCOCYTES. 
quently observed and corpuscles- 
showing the intermediate stages 
are readily detected in carefully 
prepared specimens. These 
must be differentiated from the 
blood plates. 
The cause of the destruction 
of the red corpuscles is not satis- 
factorily explained. In his re- 
port on fowl cholera, Salmon 
illustrates leucocytes surrounding 
the red corpuscles, but the marked 
diminution of the red cells was 
not determined. He _ speaks, 
however, of the pale color of the 
blood. In fresh preparations of 
the blood, portions of red cells 
may be seen within the leucocy- 
tes, those containing spindle- 
shaped granules. The determi- 
nation of the extent of this mode of destruction of the red corpuscles 
necessitates further investigation. 
TABLE SHOWING CHANGES IN THE NUMBER OF CORPUSCLES 
Fowl inoculated in the wing vein February 6 
Number of Number of 
Date |Temperature ted cor- white cor- Remarks 
(F°.) puscles puscles 
per c. mm. per c. mm, 
Feb. 6 107.4 3,744,444 21,222 Well 
vi 109 3,417,391 26,087 | Apparently well. 
8 108.2 2,784,700 55,000 Do. 
9 108.4 2,807,692 76,925 Do. 
11 107.4 3,481,818 90,909 Feathers ruffled; refuses food. 
13 110.2 | | 2,133,333 100,000 | Very quiet; comb pale. 
14 108 2,530,000 140,000 | Fowl died later in the day. 
