118 GLANDERS 
M’Fadyean has called attention to the structure of the lung 
nodules, in which he finds a central part composed of leucocytes that 
have filled the air spaces, the walls of which have disappeared as if 
by liquefaction. This is surrounded by a zone of epithelioid cells. 
A third zone surrounds this, in which the walls of the air vesicles are 
e 
Fic. 15. (a) Mass or FIBROUS TISSUE SURROUNDING QUITE LARGE BRONCHI IN 
GLANDERED LUNG; (b) GLANDERS NODULE. 
recognizable. The walls are thickened. The fourth zone is com- 
posed of air vesicles filled with a fibrinous exudate, which entangles a 
few leucocytes. Frequently the exudate is free from red blood 
corpuscles, but at times it contains much blood. In older nodules 
the third and outermost zone is composed of cirrhotic lung tissue, in 
which can be distinguished the remains of the air cells. This zone 
passes gradually into the normal tissue. In the last stage the central 
