126 GLANDERS 
hour after the injection. It is often sufficient for diagnostic purposes 
to take the temperature but four times, viz., at 9, 12, 15, and 18 hours 
after the injection, but a longer observation would be more reliable. 
aa MAU Am [AM |AALIAM. | M. | PM.) PAM) PM. 
eem|| 4 | 6 | & | so |7e | 2 | 4 8 
Bq 
LQ 
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NX 
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S 
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q 
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37 
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Fic. 23. MALLEIN REACTION. TEMPERATURE CURVES OF SIX HORSES FOR 24 
HOURS AFTER INJECTING MALLEIN. THE HORSES WERE IN ONE STABLE 
FROM WHICH A WELL DEVELOPED CASE OF GLANDERS HAD 
BEEN REMOVED. 
In healthy horses the injection of mallein, even in a much larger 
dose, produces no effect on the temperature or the general condition 
of the animal. There is produced, however, at the point of injection, 
