184 AVIAN TUBERCULOSIS 
such enormous numbers without a pronounced breaking down of the 
tissues. 
This variety can be obtained in pure cultures in about 20 per cent. 
of serum tubes inoculated directly from tuberculous lesions in fowls 
(Moore). It grows readily in glycerin agar, Dorset’s egg medium, 
in glycerin bouillon and on potato. 
Fowls inoculated in the abdominal cavity or subcutaneously with 
from one-half to one cubic centimeter of a glycerin bouillon culture 
develop either localized or generalized tuberculosis in from six weeks to 
three months, but a longer time is ordinarily necessary to kill them. 
Rabbits and guinea pigs are not readily infected by the inoculation 
of pure culture. Moore and Ward failed to produce any tuberculous 
lesions in these species by this method. 
Morbid anatomy. The lesions are widely distributed, and vary 
much in their location in different individuals. The liver is most 
frequently involved. The spleen, intestines, mesentery, kidneys, 
lungs and skin are affected in order mentioned. The appended table 
gives the distribution of the lesions in 17 cases observed by Moore. 
THE DISTRIBUTION OF LESIONS IN TUBERCULOUS FOWLS 
a ORGANS INVOLVED.* 
° & 
2| 8 ate Bet 
5 By 3G | Liver | Spleen Tates- |Mesen- lcidney | Ovary | Lungs | Bones | Skin 
Tl Ke evesex DON tihtaialle armnaighaliiialsine lltsndeullieua slattlaseuund Weenies lanes 
ON DP |i ves cl ee hpeale econ allen a's allen eal a edie oad es |Sewea ai een es XxX 
S) [1065 | MCX. cl ea saleensss awe clase adelssaseelecrs eel seaaws 
4, K_ |107 XX| XX elke cccth va] k Scensesl| eaasenenccg eevee ate averacdna [oseuoed 
5) K /|105.2 | XXX)...... DO A calll eadssccumailteraataaselicis svenaa lcs atler [MusAyalals 
6) KK OUA: V OER DOG os eral tres [eeteaire |e satin alls anata [fe aecencie [he wanecaie 
TK, [LOTD: |e seal ossas XXX} XXX]}...... DO osmefemaeetdlyinaaes 
8 Dr lapsere XxX x x x DE sclashen'al le ainarel| & aeantetell te a overess 
OF Dt |e ccsneleamealeveecelaseamaley oye SE comme sl serene bere 
10} K {108.4 | XXX PG Career [cormaceetre ear concanteal Parrareeramn) bse creer neers (Rares 
li; K |106.4 | XXX x b,¢ Paeaet en ered Pert etree peered ban ae 
12) K |107.4 | XXX) XX >. eee XXX]...... MEK ceca y| seicacecs 
13} K_ {107 OER  Sisdase sullen dytatell ace tecanel a aan bette cae deametete’S leereeroars leneteate 
14) KO L076 XN Soon aamanalll anaes leave gaccltegews «lheetaind [amie ae aaa 
16) K |1068°) XXX) XX eccealecgezslecvecalervers leomees loeaavelekoeas 
16), “D! |eiscad bzeuis esas [paeme | is acti lien ee ectcat Neteeae eed: seca | svtsannan a 
171 K_ /105 XXX| XXl...... 2,9, 4 eran ener eee rea eae ee 
*The relative numbers of tubercles are indicated by the number of Xs. XXX indicates an 
extensive invasion, XX a less number of tubercles, and X very few, Figures 43 and 44 show extent 
of lesions represented by XXX. 
The tubercles in the earlier stages of the disease, especially in the 
liver, are small greyish points varying from 0.25 to 1.0 millimeter in 
