362 DOURINE 
17. Mason. Note on the camel trypanosomiasis of Egypt, and results of first 
series of experimental drug treatment. Journ. of Comp. Path. and Therap., Vol. XXIV 
(1911), p. 47. 
18. Novy anp MacNeav. On the Cultivation of Tr. Brucei. The Jour. of Infec- 
tious Diseases, Vol. 1 (1904), p. 1. 
19. Prrriz. Observations relating to the structure and geographical distribution 
of certain trypanosomes. Jour. of Hygiene, Vol. V (1905), p. 191. 
20. Ropet er VaLLet. Contribution a I’ étude des Trypanosomiases. Arch. de 
Méd. Expér., Vol. XVIII (1906), p. 450. 
21. Smepiey. The Cultivation of Trypanosomata. The Jour. of Hygiene, Vol. V 
(1905), p. 24. 
22. Stockman. Preliminary note on a trypanosome of British Cattle. Journ. of 
Comp. Path. and Therap., Vol. XXIII (1910), p. 189. 
23. Tuiroux. Recherches morphologiques et expérimentales sur Trypanosoma 
Padde. Ann. del Inst. Pasteur, Vol. XTX (1905), p. 65. 
24. Topp. Note on immunity in cattle trypanosomiasis. Jour. of Comp. Path. 
and Therap., Vol. XXIII (1910), p. 276. 
DOURINE 
Synonyms. Venereal disease of solipeds; equine syphilis; chan- 
cerous epizoétic; breeding paralysis; epizodtic paraplegia; mal du 
coit; Beschalkrankheit. 
Characterization. A contagious affection of solipeds, transmitted 
by copulation and attended by specific lesions of the generative organs 
and nervous system, such as local venereal swellings, chancerous 
ulcers and cicatrices, dementia and paralysis. 
The disease is essentially an equine one, although the following 
species are susceptible to experimental inoculation, namely: dogs, 
rabbits, rats, mice and asses. While the horse shows the greatest sus- 
ceptibility, the ass is comparatively resistant to the infection. 
History. Dourine seems to have first been recognized in Algeria. 
It was described in 1796 by Ammon who found it in the royal stud 
at Trakehnen in Northern Prussia. It was found in Bomberg in 1817 
to 1820, in Austria and Bohemia in 1821-8, in Syria in 1821, in Swit- 
zerland in 1830, in France in 1830-32, in Siberia in 1833-40, in Italy 
in 1836, in Russia in 1843, in Poland in 1830-40, in Algiers in 1847-55. 
In Syria and Asia generally it is reported to appear perennially. It 
would seem that the original home of this disease was Asia and 
Northern Africa. 
It was found in De Witt County, Il., by Williams. It was traced 
to a percheron stallion imported from France* in 1882. In this 
*This animal had a brand mark under the mane resembling very much the letter D. 
Mohler states that it is supposed the disease had been detected and that he had been 
branded because of it before leaving France. 
