RABIES 393 
where the skin is thin, abraded or wounded, may fatally infect the 
person to whom it is endeavoring to demonstrate its affection. The 
reported cases in which rabies have developed from such inoculations 
are quite numerous. 
In most cases dogs first become dull, gloomy, morose, seeking 
solitude and isolation in out-of-the-way places or retiring under pieces 
of furniture. But in their retirement they cannot rest, they are 
uneasy and agitated, they lie down and assume the attitude of repose, 
but in a few minutes they are up walking about “‘seeking rest, but 
finding none.” Occasionally this restlessness may disappear for a 
time and the animal becomes lively and affectionate; oftener it sinks 
into a sullen gloominess from which even its master’s voice rouses it 
but temporarily. At this period dogs may have aberrations of the 
senses which cause hallucinations and lead them to think they are 
being annoyed by something or that some animal or person is endeay- 
oring to injure them. They crouch ready to spring upon the enemy; 
they rush forward and snap at the air; they throw themselves, howl- 
ing and furious, against the wall as though they heard sounds beyond 
it. 
While at first the affected dog may not be disposed to bite, it 
becomes more dangerous as its hallucinations and delirium increase. 
Food is taken at first if it is something that can be swallowed with- 
out mastication, otherwise it is soon dropped. Difficulty in swallow- 
ing is an early symptom. Mad dogs have no fear or dread of water, 
they continue to drink until paralysis prevents them from swallowing. 
When the furious symptoms appear, the dog may leave his home 
and start upon a long chase with no apparent object in view other 
than to be traveling. He trots at a rapid pace, eyes haggard and 
tail depressed. He is indifferent to the surroundings. He often flies 
at and bites persons whom he meets, but usually he does not search 
for them or even notice them if they remain quiet. Dogs in this 
condition may travel many miles and finally drop from exhaustion 
and die. Often after an absence of a day or two they return to their 
homes, exhausted and emaciated, presenting a most forlorn and miser- 
able appearance. Those who have pity for such an animal and try 
to make it clean and comfortable are in great danger of being bitten, 
as the disease has advanced to a point where the delirium or insanity 
is most marked and where a treacherous bite is most common. 
If the animal, instead of being allowed to escape, is kept confined, 
the paroxysms of fury are seen to occur intermittently or, in the 
