468 CANINE DISTEMPER 
ent exudate may appear. The exuded matter consists of pasty 
mucous or dirty yellowish pus. This exudate collects under the lower 
eyelids, chiefly at the inner canthus of the eye, and soils the edges of 
the eyelids, upon which it frequently dries and causes the lids to 
adhere, especially during the night. Ulcers form on the cornea in 
consequence of the action of the accumulated and decomposing pus 
and the patient wiping and rubbing the eyes with its paws. The 
epithelium of the cornea sometimes suffers more or less from shallow 
flat lesions which give the surface of the cornea a rough and uneven 
appearance. Frequently smaller and deeper ulcers form especially 
toward the center of the cornea. 
In other cases, there is a diffuse, parenchymatous keratitis which 
renders the cornea, to a considerable extent, opaque and gives it the 
appearance of ground glass. These extensive opacities sometimes 
develop in a comparatively short time. This affection of the cornea, 
the so-called ‘“‘distemper of the eyes,” is frequently the only evidence 
of distemper with the exception of the high temperature. 
There may be vomiting, well marked congestion and dryness of the 
oral mucosa. There is usually constipation at first, but later a 
diarrhea in which the feces, as a rule, are very fetid, often slimy and 
frothy. Hemorrhagic intestinal catarrh sometimes exists. The urine 
frequently contains albumin and bile pigment, especially when the 
patient is weak or in an advanced stage of the disease. 
The nasal discharge is serous at first, mucous or purulent later on. 
It is followed by sneezing, panting and a nasal pruritis, which causes 
the animal to rub its nose with its paws. The purulent discharge 
from both nostrils may be very copious. It is sometimes mixed with 
streaks of blood, and varies in color from a dirty yellow to a dirty 
green. Later, it may become fetid and even watery. Ulcers may 
appear on the nasal mucosa. 
Laryngeal catarrh usually accompanies the nasal catarrh and mani- 
fests itself by a cough, which comes on in paroxysms and which is at 
first hoarse and dry, but later moist and accompanied by a discharge 
of phlegm. The cough excites vomiting. The catarrh spreads from 
the larynx to the trachea and bronchi. The resulting bronchitis is 
followed by an increased rate of breathing and manifests itself by a 
cough and hoarse, sharp, vesicular, respiratory murmurs. Fre- 
quently there is a catarrh of the mucous membrane of the smaller 
bronchi. There may be difficulty in breathing and a feeble cough 
which the patients try to suppress. The cough may be excited by 
