INFLAMMATION. 17 
connective tissue, with cells and basement substance in varying pro- 
portions. 
To what changes does this form of inflammation give rise in dif- 
ferent kinds of tissue ? 
In connective tissue it produces thickening and adhesions. In the 
viscera there is a growth of new tissue interfering with the functions 
of the organ, compressing the visceral cells and causing their degen- 
eration. 
In mucous membranes the stroma or corium is thickened either dif- 
fusely or in the form of polypoid growths, and the epithelial layer of cells 
may be thicker or thinner than normal. The mucous glands may be atro- 
phied, hypertrophied or cystic, and their secretion increased or diminished. 
To what is tubercular inflammation due ? 
To the influence of the presence and growth of the tubercle bacillus 
or to its products, or to both influences combined. 
What is the nature of the inflammation ? 
It is of the exudative or productive type, or of both combined. 
There are the usual products of these two forms of inflammation and 
also the production of a new tissue called tubercle tissue. 
Describe tubercle tissue. 
It is composed of a basement substance forming a meshwork enclos- 
ing large polygonal cells and giant cells. It occurs in small spherical 
masses called miliary tubercles, or may occur as a diffuse infiltration. 
This form of tissue is of very low vitality and quickly dies, undergoing 
cheesy degeneration, followed sometimes by caleareous degeneration. 
Describe syphilitic inflammation. 
It is an inflammation caused by the poison of syphilis, probably due 
to the growth of some specific bacterium, the nature of which we are at 
present ignorant. The inflammation is of the exudative or produc- 
tive type, or of both combined. 
What is the type of tissue produced in this form of inflammation ? 
There is a production of new connective tissue, especially in the 
viscera, taking the form of an interstitial inflammation. Also there is 
produced, in connective tissue and in the viscera, a small round-cell 
and granulation tissue often in the form of circumscribed masses called 
gummy tumors. These masses when occurring in mucous membranes 
are called mucous patches. 
