Bacteriology 



395 



fectious and not toxic in character though brought about by filtered 

 fluid. 



The virus resists freezing but is readily destroyed by heating to 

 45°-50°C. for half an hour. 



Various attempts were made by Kraus and Wernicke,* Lentz 

 and Huntemiillert and Marks J to infect rabbits with the virus, but 



Fig. 136. — Micro-organism causing epidemic poliomyelitis. 3, Separate glo- 

 boid bodies, X 1000; 4, aggregated masses of globoid bodies, X 1000; 5, chains 

 and pairs of globoid bodies, X 1000; 6, chains of globoid bodies compared with 

 Streptococcus pyogenes, X 1000; 7, agar fragment showing pairs of globoid bodies 

 compared with Streptococcus Pyogenes, X 1000 (Flexner and Noguchi, in Journal 

 of Experimental Medicine). 



though some successes were reported, there seems to be no develop- 

 ment in the rabbit of lesions or disturbances resembling the char- 

 acteristic lesions and symptoms of acute anterior poliomyelitis in 

 man and the monkey. 



* "Deutsche med. Wochenschrift," 1909, xxxv, 1825; 1910, xxxvi, 693. 

 t "Zeitschrift fur Hygiene," 1910, lxvi, 481. 

 t"Jour- Exp. Med.," 1911, xiv, 116. 



