Zur Nedden's Bacillus 427 



ZuR Nkdden's Bacillus 



This bacillus was the only organism that Haupt* was able to 

 isolate from a neuroparalytic with confluent peripheral ulcera- 

 tions of the cornea. It seemed to be identical with an organism 

 that zur Nedden had found previously in a case of corneal ulcera- 

 tion in the clinic at Bonn. 



Morphology. — 'It is a tiny bacillus, less than i /^ in length, slightly 

 curved, generally single, but sometimes in pairs and short chains. 

 It is not motile, has no flagella, forms no spores. 



Staining. — It stains ordinarily, but not by Gram's method. 



Cultivation. — It is easily cultivated upon the ordinary laboratory 

 media, the cultures being without characteristic peculiarities. 

 Gelatin is not liquefied. Milk is coagulated. Acid but no gas is 

 formed in glucose media. A thick yellowish growth appears upon 

 potato. No indol is formed. 



Pathogenesis. — Corneal ulcers were formed in a guinea-pig 

 after artificial implantation in the corneal tissue. 



Miscellaneous Organisms in Conjunctivitis 



In addition to the foregoing organisms, others not infrequently 

 make their appearance as excitants of conjunctivitis. The most 

 frequent of these being the pneumococcus, the most dangerous, the 

 gonococcus. The former produce a severe conjunctivitis, with 

 the formation of a false membrane, the latter the well-known 

 blenorrhea and ophthalmia neonatorum. Streptococci, diphtheria 

 lacilli, staphylococci, meningococci, colon bacilli. Bacillus pneumonia 

 (Friedlander), and other organisms have occasionally been found 

 and appear to be responsible for a few cases of conjunctivitis. 



* "Inaugural Dissertation," Bonn, 1902. 



