554 



Sleeping Sickness 



elusion that the essential lesion is an extensive meningo-encephalitis. 

 To the naked eye, there are scarcely any legions in sleeping sickness, 

 except the enlargement of the lymph nodes, and even in the nervous 

 system when one looks with care, there is but little to be seen. The 



P'ig. 214. — Photomicrograph of an eosin-methylene-blue-stained section; - 

 1000 diameters. Shows tr3T)anosomes about a small vessel of the cortex of the 

 brain (Wolbach and Binger, in "Jour, of Med. Research"). 



histological examination of the nervous tissues, on the contrary, 

 shows that in both the brain and spinal cord there is proliferation 

 and overgrowth of neuroglia cells, especially those connected with 



Fig. 215. — Photomicrograph of 

 a Giemsa-stained section; 1000 

 diameters, showing a trypano- 

 sonie deep in the cortex of the 

 brain (Wolbach and Binger, in 

 "Jour, of Med. Research"). 



(2) (0 



Fig. 2i6.-;-Trypanosomagambiense. 

 Formation of the latent stage and 

 transformation of the latent stage into 

 a trypanosome (after Guiart). 



the subarachnoid space and the perivascular space, with accumula- 

 tion and probably proliferation of lymphocytes in the meshwork. 

 Wolbach and Binger found that the trypanosomes actually escape 

 from the blood-vessels and make their way into the nervous tissue. 



