THE author's investigation. 273 



These appearances in the upper lobes were due to septic pleuro-pneumonia. 

 They closely resembled, and were supposed to be due to, infectious 

 pleuro-pneumonia. They were, however, found identical with the con- 

 dition observed in septic pleuro-pneumonia in calves, and the disease was 

 not conveyed by infection to other animals in the same stall. Scattered 

 through the other lobes of both lungs were white, mostly firm, nodules 

 raised above the level of the surface of the lung. They were surrounded 

 by a, zone of congestion, and in some cases sections were composed of 

 indurated, in others of friable, lung tissue. In the posterior part of the 

 right upper lobe there was a recent infarct. The bronchial glands at the 

 roots of each lung were enlarged to two or three times their 'natural size, 

 and were firm and hard on section. The parietal surface of the pericardium 

 was covered with recent adherent lymph. The visceral surface of the 

 pericardium was normal. Along the external surface of the aorta were 

 chains of enlarged lymphatic glands connected by dilated lymphatic 

 vessels. These glands were dark red or purplish in colour, from haemor- 

 rhage into their substance. The heart was normal, and the endocardium 

 not stained. There were chains of red glands on the oesophagus similar 

 to those along the aorta. The appearance of the mesenteric glands was 

 very striking. The mesentery, along the lymphatic vessels, was dotted 

 with glands, varying in size from a large shot to a pea, which were deep 

 red or prune-coloured. In addition, there were here and there enlarged 

 glands without hsemorrhage into their substance, and greyish in colour. 

 There were scattered petechiae on the spleen. The kidneys were firm 

 on section, and there was marked congestion in both, while it was more 

 pronounced in one kidney than the other. The liver was congested, the 

 congestion being more marked in patches. 



Sections from the consolidated upper lobes showed under the micro- 

 scope thickening of the pleura and infiltration with round cells. The 

 exudation filled the alveoli, and was breaking down in some cases in the 

 centre. The vessels were injected, and there were hsemorrhages into the 

 alveoli. The periphery of the lobules was infiltrated with round cells. 

 In sections of the kidney there was slight infiltration around glomeruli 

 and arterioles with round cells ; the epithelium in the convoluted tubules 

 was granular and disintegrating ; there was haemorrhage in the straight 

 tubules, and engorgement of vessels. In sections of liver the inter- and 

 intra-lobular vessels were engorged ; there were interlobular collections 

 of round cells displacing the liver cells, and the interlobular connective 

 tissue was infiltrated with round cells ; the liver cells were granular and 

 cloudy. 



There can be no doubt from the symptoms and post-mortem 

 appearances that this calf had been suffering from septicaemia as 

 the result of introducing the septic virus and crust subcutaneously 

 in the groin. 



The two Wiltshire cows were killed, and there was nothing of 

 importance to note in one, but in the other an incision into the 

 udder revealed an enormous abscess. 



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