NO TES. 293 



bers of secondary tubules grow out from the principal duct of the 

 hypophysis, and acquire ciliated funnel-like openings into the 

 peribranchial chamber ; subsequently Herd.man (Proc. Roy. Soc. 

 Edinburgh, XII. 1S82-84. p. 145) found that in this form the 

 dorsal tubercle, or opening of the hypophysis into the buccal cavity, 

 is sometimes absent. In Ciona intestinalis I have found in young 

 individuals an obliteration of the lumen of the hypophysis between 

 the proximal and the distal portions. In other cases, as in Appen- 

 diciilaria, the glandular portion of the hypjophysis may be reduced 

 or absent. 



On the subject of the Ascidian hypophysis, the following papers 

 should also be consulted : Sheldon, Lilian. Note oti the Ciliated 

 Pit of Ascidians and its Relation to the Nerve-ganglion and So- 

 called Hypophysial Gland. Quarterly Jour. Micro. Sc. XXVIII. 

 1888. pp. 131-148. HjORT, JOHAN. Ueher den Entwicklungs- 

 cycliis der Zusammengesetzten Aseidieti. Mitth. Zool. Stat. Neapel, 

 X. 1893. pp. 584-617. Metcalf, Mayxard M. The Eyes and 

 Sub7ieural Gland of Salpa. Baltimore, 1893. (Published as 

 Part IV. of Professor Brooks's Monograph of the Genus Salpa.) 



4. (p. 290.) The most complete presentation of the Annelids- 

 theory is contained in the classical Monographie der Capitel- 

 liden des Golfes von Neapel, by Dr. Hugo Eisig. It is needless 

 to add that this monograph will command the gratitude and 

 admiration of zoologists to the end of time. 



