^64 



INFECTIVE DISEASES. 



of scarlet fever in man, twice in association with certain other 

 micro-organisms, and three times alone. The micro-organisms were 

 isolated by inoculating tubes of nutrient gelatine, solidified obliquely, 

 by streaking the surface with blood taken from the finger, the arm, 

 or the heart after death. Those cases from which the organism was 

 obtained were all cases with ulcerated throat, and the culture 

 experiments, from the hving patient, were made on or about the day 

 at which the temperatiu-e was at its maximum. 



Klein x-egards this streptococcus as the actual cause of scarlet 

 fever in man. 



The author, Raskin, Holmes, and others who have investigated this 

 subject agree with the conclusions of Frankel and Freudenberg. The 

 aiithor is convinced that the streptococci in suppuration, puerperal 

 septicaemia, pyasmia, and septicsemia, and in certain cases of measles, 

 scarlatina, and diphtheria, are identical ; and from overwhelming 

 evidence we are justified in concluding that — (1) The nature of 

 the contagium of scarlet fever is unknown. (2) The streptococcus 

 regarded by Klein as the contagium is the Streptococcus pyogenes. 



