COW-POX. 313 



inquiries wei-e made in 1857, it was found that Mr. Donald 

 Dalrymple, of Norwich (on two occasions), Mr. Beresford, of Nar- 

 borough, iu lieicestershire, Mr. Gorham, of Aldeburgh, Mr. Alison, 

 of Gi-eat Eetford, Mr. Coles, of Leckhampton, Mr. Rudge, of 

 Leominster, and one or two othei-s, had met with outbreaks of 

 cow-pox. 



In 1885 cow-pox was discovered by the author in Wiltshire. The 

 publication of the fact led to the recognition of the disease in the 

 same year in many parts of England, and cases were met with in 

 man iu 1888 by Mr. Forty in Gloucestershii-e, and by Mr. Bucknill 

 near London in 1894. 



In Italy, cow-pox was found by Sacco in the plains of Lombardy 

 in 1800, and by other practitioners in 1808-9. In 1812 it was 

 observed at Naples by Miglietta; in 1830 in Piedmont ; and in 1832 

 and 1843 at Rome, hy Dr. Maceroni. More recently, several out- 

 breaks of cow-pox have been met with in this country, and the stocks 

 of vaccine lymph renewed. 



In France, in 1810, cow-pox was found in the department of 

 La Meurthe, and in 1822 at Clairvaux ; at Passy, Amiens, and 

 RambouUlet in 1836 ; at Rouen in 1839 ; at St. Ilhde, at St. Seine, 

 and at Pervlhac, in 1841 ; in 1842 at Pagnac ; in 1843 at Deux 

 Jumeaux, where, during the previous thu'ty years, several fresh 

 stocks of lymph had been raised and circulated. The disease occurred 

 in a cow belonging to M. Majendie in 1844, and it was found at 

 Wasseloune, in the department of Bas Rhin, in 1845 ; it occurred in 

 three other departments iu 1846 ; at Rheims, and in the department 

 of Eure et Loire, in 1852 ; in the arrondissement of Sancerre, and at 

 Beziers in 1854; and at Guyonville in 1863. It broke out on farms 

 in three %'illages near Nogent in 1864 (the disease was introduced by 

 newly purchased cows ; milkers were infected, and from one of these 

 milkers a lymph stock was estabhshed); it also occurred in 1864, at 

 Petit Que\-ilh-, near Rouen; and in April 1866 at Beaugency ; in 

 1881 at Eysines, near Bordeaux, and again at the same place in 

 1883 ; and in 1844 at C6rons. 



In Germany, as soon as attention had been drawn to the disease, 

 cow-pox was frequently discovered. There were as many as tliirty- 

 eight outbreaks reported in one year in Wurtemberg. 



It is hardly necessary, after reciting these instances, to insist 

 that cow-pox is far from being a rare disease, as many have sup- 

 posed who ai-e unacquainted -with the literature of the subject and 

 unfamiliar with the appearances of the natural disease in the 



