SWINE FEVER. 349 



Bucld first pointed out that this diseasB might be compared 

 to human typhoid, both diseases being attended by a pecuKar 

 ulceration of the intestinal follicles ; but the diseases are not to 

 be considered in any sense identical or interchangeable. 



Bacteria in Swine Fever. 

 — In 1877 Klein published a 

 research in a Report to the Local 

 Government Board, in which 

 he claimed to have discovered 

 bacilli characteristic of the 

 disease. They weve described as 

 similar to Bacillus subtilis, or 

 BaciUus anthracis, but smaller I-'ig. 138. -Bacillus oi^SwiNE-rKVER 



in size. These bacilli developed 



into long leptothrix filaments, and formed spores. It was further 

 asserted that on inoculation, cultures produced lesions indicative of 

 swine fever ; the bacilli were also pathogenic in mice and rabbits. 



Later this bacillus was re- 

 nounced in favour of another. 

 In the following year Det- 

 mers described a bacillus, but 

 subsequently renounced it in 

 favour of a micrococcus. 



In 1882 Pasteur maintained 

 that the virus of swine fever in 

 France (rouget) was a dumb-bell 

 Fig. 139.— Bacillus No. 2. rBOM a micrococcus, which produced the 

 Pbbpabation of Bkonchial Mucus ^^^^^ ^q^^ j^ pigeons as the 



microbe of fowl-cholera. Though 

 rouget or swine mea.sles is probably a different disease, the occurrence 

 of this micro-organism is of interest in this connection. 



In 1883 Klein again investigated swine fever, and discovered 

 Bacillus No. 2, and maintained 

 that these bacUli were found in ■'^ •< 



the blood, in the peritoneal and -^ ^ ^ 



bronchial exudations ; and in the ^ --■ ' j 



air vesicles of the lungs, in the '■"^'' -.in- 



form of leptothrix filaments ten 



. j_. ,11 ,1 ,. Fig. 140.— Bacillus No. 2. Feom an 



or twenty times the length of artificial Culture. (Klein.) 



single rods. Cultivations were 



made on solid media. The organisms in these cultures were minute 

 rods actively motile, occurring singly or forming chains, two or three 



