RESTOilATlVE AGilNTS. 3j 



Liquor Pepsini (U. S. P.), solution of pepsin, li- 

 quid pepsin. Dose: D., fl. 3i.-ij. (Contains sac- 

 charated pepsin 40, hydrochloric acid 12, glycerin 

 400, water enough to make 1,000.) 



Extractum Pancreaticus, or pancreatin, which 

 should contain the four pancreatic ferments. Doses: 

 H., 3ss.-iss. ; D., gr. iij.-v. 



Lactopeptin, a powder containing pepsin, pan- 

 creatin, diastase, lactic acid, and hydrochloric acid. 

 Dose: D., gr. v.-xv. 



Incompatibles. — Alkalies and many mineral salts 

 precipitate pepsin, while alcohol destroys its activ- 

 ity. Alkalies promote the action of pancreatin. 



Physiological Action.— Pepsin digests the pro- 

 teids or nitrogenous principles of the food (albumin, 

 casein, fibrin, etc.), converting these into peptones for 

 assimilation. Pancreatin, in addition to this, also 

 emulsifies the fats and oils, and may be itself digested 

 by pepsin ; hence it but seldom reaches the duodenum 

 in its original form. Papain is a powerful digester 

 of fibrin and will act in solutions of any reaction, 

 while pepsin requires an acid solution. 



Therapeutics. — The internal use of pepsin and 

 pancreatin is limited to young herbivora while receiv- 

 ing milk, and to dogs or other camivora. 



Pepsin is beneficial in atonic dyspepsia, gastralgia, 

 anaemia, chlorosis, and the diarrhoea of calves, foals, 

 and dogs. It may be added to nutritive enemata to 

 assist in their assimilation, the rectum not being 

 a digestive organ. Acidulated solutions may be 

 injected into the substance of morbid growths, 

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