148 VETERINARY MATERIA MEDICA. 



miaous matters, starch, oil, and an alkaloid, known 

 as eserine, physostigmine, or calabrine (some writers 

 claim a second alkaloid for the Calabar bean, and 

 designate this as calabarine). 



Chief Preparations. — Faba Caldbarica, Cala- 

 bar bean (powdered). Dose: H. and C, gr. xv.- 

 XXX.; D., gr. ^. 



Physostigmince Salicylas, physostigmine (eser- 

 ine) salicylate. Colorless, shining, acicular, or short 

 columnar crystals, gradually turning reddish when 

 long exposed to light and air, odorless, having a bit- 

 ter taste and a neutral reaction. Soluble ,in 130 

 parts of water and in 13 parts of alcohol. The aque- 

 ous, also alcoholic solution, when exposed to light 

 for a short time, turns reddish and should be dis- 

 carded. 



Physostigmince Sulphas, physostigmine (eserine) 

 sulphate. In appearance and properties resembles 

 the salicylate. Dose of either of these salts, subcu- 

 taneously or intratracheally : Dose: H., gr. i.-iss. ; 

 D., gr. iV-A; per os, H., gr. ij.-iij.; D., gr. ■^^-^. 



Lamellce Physostigmce, disks of physostigmine, 

 medicated disks. Used locally on the eye, each con- 

 taining gr. -jpinnr- 



Physiological Action.— -Physostigma is a pow- 

 erful muscular stimulant and direct spinal paralyzer, 

 capable of producing a complete general paralysis 

 and abolishment of the reflexes without affecting 

 muscular irritability or the brain. Secretions are 

 stimulated, nausea and vomiting are induced, par- 

 ticularly in carnivora. Its cathartic properties are 



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