160 TfiTERINARY MATERIA SlEDICA. 



Therapeutics. — The nitrites are employed in an- 

 gina pectoris, asthma, epilepsy, spasmodic cough, 

 vomiting and nausea, puerperal convulsions, chronic 

 interstitial nephritis, tetanus. 



ANTIZYMOTICS, ANTIPYRETICS, ANTI- 

 PERIODICS. 



The cinchona alkaloids are the most powerful of 

 these, and have already been described. 



Antipyrinum — Antipyrin. 



(Syn. — Phenazone, Methozine, Analgesine, Dimethyl- 



phenylpyrazolon.) 



A synthetical base, vsrhich forms salts analogous to 

 the ammonia compounds, and is a product of the de- 

 structive distillation of coal tar. It may also be 

 prepared synthetically. It occurs as a whitish, crys- 

 talline, odorless powder, which combines with acids 

 to form salts ; slightly bitter taste, soluble in its own 

 weight of water, in alcohol, and chloroform, but not 

 so readily soluble in ether. It is best given alone, as 

 it is incompatible with many drugs, the more impor- 

 tant of which are tannic and prussic acids, chloral hy- 

 drate, preparations of cinchona bark, ferric salts in so- 

 lution, infusions and tinctures containing tannin and 

 quinine, tincture of iodine, and corrosive sublimate. 



In action it is a powerful antipyretic, antirheu- 

 matic, antineuralgic, antiseptic, and haemostatic. 

 Large doses are apt to irritate the gastro-intestinal 

 mucous membranes, and in the dog to cause vomit- 



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