154 Specific and Contagious Dtseases. 
soon become dark-coloured, or black, emitting an 
offensive odour. Severe colic accompanies the changes 
referred to, and great depression is evident, the pulse is 
now running down, temperature declines rapidly, and the 
animal dies in agony. When this is the case a portion 
of the intestine may be observed, on post-mortem ex- 
amination, to be firmly contracted, congested, and 
probably infiltrated, as well as ulcerated. Some cases 
do not proceed thus far, death arising from blood- 
poisoning and coma. 
Eczema of a severe form is another serious compli- 
cation. Innumerable pustules form over the body, or 
perhaps only over the surface of the belly, some of which 
are so small as to resemble the puncture by a pin; 
others are larger and well defined, while a third form 
consists of a confluence or union of these which raise the 
cuticle over a wide area as a large swelling. The system 
then suffers violently from pain, shock, and an enormous 
drain, and from this period the patient becomes weaker, 
and finally dies in the majority of cases. In milder 
forms the pustules mature, burst and discharge their 
contents, which proves the welfare of the system, but in 
the severe states the poison is re-absorbed, to the great 
detriment of the circulation. 
Treatment.—This is of two kinds, preventive and 
remedial. With regard to the first, vaccination or 
inoculation with the eye or nasal discharges, has been 
set forth as all sufficient. Upwards of forty years ago we 
had the privilege of assisting the late Professor Barlow, of 
Edinburgh, in a great number of trials for the sole 
purpose of testing the value and usefulness, if any, of the 
operation. It is almost needless to state the results were 
mi, and to the present day that experience has been 
repeatedly verified. If, however, we regard the presence 
of bacteria as the sole cause, the use of cultivated fluids 
may solve the mystery. Let the sick be rigidly kept 
apart from the healthy, observing all necessary rules of 
sanitation, with a judicious employment of antiseptics of 
known value, of which ‘Sanitas” preparations take 
