160 Specific and Contagious Diseases. 
develops into a succession of equally abortive howls. 
This is most common at night after the routine of bustle 
and noise is stilled, and is consonant with the usual re- 
cuperative efforts of the system at this season, which have 
the tendency to aggravate existing disease. At this stage 
also signs of local: irritation may be present, the cause 
being the cicatrix of a former wound inflicted by another 
dog suffering from the disease. He licks at first, but 
eventually bites or even tears the skin which at this part 
exhibits the gangrenous stage. This is the inoculation 
point, which, as a result of the introduction of the virus 
heals but imperfectly, and is subject to the consequences 
of irritation and ulceration, one of Nature’s efforts to rid 
herself of the poison. The issues are constantly fatal, 
death taking place from two or three days in some of the 
most acute cases, or it is otherwise delayed until about the 
seventh day. 
The Post-mortem Appearances in fully developed cases 
are remarkable. The body very shortly enters into a 
state of decay. At the back of the mouth, and within 
the stomach, foreign bodies of the most strange character 
are found, as sticks, stones, dirt, feces, bits of iron, tin, 
leather, &c. The back of the tongue and the mouth, 
with the lining membranes of the windpipe, also those of 
the pharynx and larynx, are highly congested and streaky, 
particularly about the epiglottis, and the vocal chords are 
not uncommonly ulcerated. The salivary glands are in- 
volved in the general congestion, which extends to the 
stomach and intestines, portions of which exhibit patches 
of extravasated blood, some of which have already entered 
on the ulcerative stage. As a result of this process within 
the stomach, considerable effusion ‘n the form of a coffee- 
coloured fluid—-abnormal blood material—is present 
in addition to the usual heterogeneous accumulations. 
Blood spots are found upon the heart, pleura, peritoneum, 
and elsewhere. The spleen, liver, and lymphatic glands 
generally are enlarged by congestion ; also the substance 
of the brain, medulla, and spinal chord with their several 
coverings. In addition, there are indications understood 
only by the scientist, assisted by a powerful microscope, 
