Specific and Contagious Diseases. 169 
the digestion was disturbed; fluctuating tubercular 
tumours were discovered in the abdomen, and on testing 
the lungs the sibilant rdle was distinctly heard. There 
was no cough, and still the chest was elastic and without 
dulness on percussion. An injection of tuberculin was 
made at 1 P.M. At11.30 P.M. the temperature had fallen 
to 99° F., and at 12.30 A.M. it was 98° F. Shortly after- 
wards the animal died. An examination revealed the 
presence of tubercular nodules in the lungs, varying in 
size from a pin’s head to larger areas, but they were firm, 
thus accounting for the absence of rales. Bacilli were 
found in the mucus of the bronchial tubes, and the 
tubercular areas consisted mainly of epithelioid and 
spindle-shaped cells. A few bacilli were also found. 
‘The stage of caseation does not appear to have com- 
menced. Miliary tubercles studded the mentum, liver, 
and spleen. The mesenteric glands were enlarged, 
hard, and fibrous, and in one a large abscess existed. A. 
few bacilli were also found. The absence of caseation, 
or cheesy degeneration, so common: in this disease, is 
fully accounted for by the action which resulted in the 
free development of fibrous tissue around the diseased 
points. The Professor concludes with a suggestion as 
to-the value of tuberculin as a diagnostic in this disease 
of the dog. 
Variola or Smad// pox in canine animals closely re- 
sembles the form usually observed in mankind as well as 
the sheep ; one of the means of its introduction being 
the consumption of the flesh of sheep dying of the 
disease. It appears in the usual forms of mildness or 
malignancy ; it may be discrete or separate, confluent or 
running together, and in further stages are those of 
erythema, nodule, vesicle or bladder, and pustule, the 
latter assuming the flat or concave surface from the usual 
internal changes. Subsequently desquamation proceeds, 
leaving hairless spots, which are hollow or concave scars 
or “pits.” The thin skin of the belly and insides of the 
fore-arms or thighs are especially invaded. 
The Symptoms, in addition to those already enumerated, 
consist of febrile disturbance from the first, which 
