the skin, seem to be the most advantageous treatment at the beginning, 
and when there are no cracks on the skin. Cadéac recommends the treat- 
ment used in anasarca: at the very outset, before the appearance of the 
swellings, bleeding gives the best results; later, the sulphate of soda, 
alcohol, wine, nitrate of potash, scarifications and vapor baths. Irritating 
frictions (charges, ammoniacal liniment, spirits of turpentine) made on the 
swellings might be used. 
If gangrene occurs, the sloughing of the eschars is to be assisted, and 
the wounds following to be dressed antiseptically. 
V. 
ACNE. 
The papulo-pustular eruptions due to the inflammation of sebaceous 
glands of a non-specific nature are met in subjects of the various domestic 
species, but more frequently in horses and dogs. Produced by multiple 
causes, they seem to be especially the result of mechanical irritations to 
which the pilo-sebaceous follicles are particularly sensitive. 
In horses recently clipped, it is common to observe, on the regions 
supporting the harness, confluent patches of acne. Short, rough hair 
transmits the pressure to the hairy bulbs, act as irritating thorns, and thus 
promote a papular or pustular inflammation. On the superior border of 
the neck, where the collar rests, the hair of the mane, cut very short, 
may also irritate the pilo-sebaceous follicles and bring on an eruption 
of acne, which may be complicated with extremely painful cores. (See 
Cores.) In dogs, acne may be seen in the most different regions ; some- 
tiraes, in serious cases, it becomes generalized. It is rare in ruminants. 
When the cause of acne is known, the first rule of treatment is to relieve 
or remove it. On horses, soft pads should be placed between the har- 
ness and the diseased part. Since dirt keeps up the disease and pro- 
motes its spreading, repeated tepid antiseptic washings should be given, 
and after careful drying the parts should be covered with glycerine, car- 
bolated or borated vaseline. When the disease is recent, these means 
are sufficient. On old cases, when the skin is indurated, mercurial oint- 
ment can be advantageously used. 
In the case of dogs, for recent acne, salicylic lanolin (salicylic acid 20, 
lanolin 80-100) is better; but for old acne, cresyled boric acid (creoline 
1, boric acid 40). Before their application, the purulent pimples should 
be opened and the diseased surfaces well cleaned. 
