PARASITE OF KALA-AZAR 



79 



of a possible cycle in an insect host. That this phase of the 

 life history of the parasite may normally be omitted is never- 

 theless quite possible. 



Human Cycle. — After entering the human body, the para- 

 sites probably utilize the blood and lymph streams to obtain 

 transportation to all parts of the body, but do not Hve free in 





Fig. 14. Parasites of kala-azar, Leishmania donmani; A, isolated parasites 

 from spleen; B, dividing forms from liver and bone marrow; C, spleen cell with 

 parasites ; D, group of cells with parasites ; E, parasite ingested by leucocyte ; F-0, 

 from cultures; F and G, early stages after ingestion; H, large dividing forms; /, 

 development of flagellum; /, small flagellated form; K and L, flagellated Herpe- 

 tomonas forms; M and A'', unequal division; 0, parasites resulting from unequal 

 division shown in M and A''. X about 1500. (After Leishman.) 



