MORBID ANATOMY 



177 



circular, slightly projecting 

 masses, stained yellowish or 

 blackish or both in alternate 

 rings, or they may be slightly 

 depressed and somewhat ragged 

 in outline. When the superficial 

 slough is scraped away many ul- 

 cers show a grajnsh or white base. 

 A vertical section reveals a 

 rather firm neoplastic growth, 

 extending usually to the inner 

 muscular coat. When sections of 

 such an ulcer are stained with 

 aniline dyes and examined under 

 the microscope, the submucous 

 tissue is verj' much thickened, 

 infiltrated with round cells and 

 containing a large number of di- 

 lated vessels. Resting upon this 

 thickened submucosa, is a line of 

 verj' deeply stained amorphous 

 matter and upon this is situated 

 the necrotic mass which fails to 

 retain the coloring matter and 

 which is permeated b}- an im- 

 mense number of bacteria of vari- 

 ous kinds. Frequenth' the eggs 

 of trichocephalus are imbedded 



in the slough. _ „^, . ^. 



^ Fig. 41. Splc'CHs of fif^s 0/ 



The extent of the submu- //„• sai,u- a^r ,- (a) dead jnvu hog 

 cous infiltration depends upon cholera: [h) normal, [killed in 

 the age of the ulcer. In old /"'"''/''')■ 



ulcers it contains many newly-formed capillaries and e\-idences 

 of the formation of connective tissue are present. The capil- 

 laries may extend to the ver}- edge of the border where the 

 slough begins. The latter may have been partly shed, leaving a 

 smooth line bounding the cicatricial tissue. The submucous in- 

 filtration gradually disappears toward the periplierj' of the ulcer 



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