THE PATHOGENIC HEMOSPORIDIA 289 



have come to the same conclusion, that the drug acts directly upon the 

 parasite, killing it with more or less distinct evidences of disintegra- 

 tion of the organism. Marchiafava and Celli conclude that the treat- 

 ment is most effective during the period of sporulation and upon the 

 young stages of the organism, and practically without effect during 

 the period of pigment formation and full growth of the schizonts. 



19 



