THE RELATIONS OF METABOLISM TO FOOD-SUPPLY. I1f 
Meat Faten Gain (+) or Loss (—) of Fat. 
Date of Experiment. Pee Devs According to Pet- According to 
tenkofer & Voit. Pfitiger. 
Grms. Grms. 
Feb. 19,1861............. 1800 + 1.4 —35.8 
Aer Bs eon (reat Cocueenlanate . 2500 +56.7 + 3.98 
Chi 4, 1862). sic sede sieies 1500 + 3.4 —29.3 
e221, hee elves aR ab sea vets 1500 + 7.3 —23.4 
Aon 7, en eeus sens se 1500 +34.4 + 3.7 
Se UD Ae Rare tsar seamen 1500 +20.7 —11.1 
hE ceaaie atelier 1500 +35.9 + 3.8 
SE NG 8S ssskes the ors laces 1500 +22.9 — 8.4 
Aug: 6," assokwewew ees 1500 + 8.7 —13.5 
OB aaa ask yale eG 1500 +17.4 — 8.3 
Feb. 20, 1863............. 1500 0.0 —31.6 
Oe DB BE ay astaee us calucela aoe 1500 + 9.9 —22.1 
OD OE es spies aaretacot ae 1500 + 2.1 —24.4 
Mochi 4,0 8 new ew tee ee 1500 +14.3 —16.9 
Apr. J, AO” praia Baie ea-aes 1500 0.0 —31.8 
Sane Sams ia oren een Re 1500 +13.8 -—17.5 
CEST Ee ss Sala esare ta ual 1500 + 9.0 —22.0 
June: Vy coca cead 1500 +12.7 —13.0 
SE AAS. POEs fate taste an eines 1500 +26.3 — 5.4 
Oe nm dGgees wags 1500 +29.1 — 2.9 
Be Dh EE ia ccs Fea a neets 2000 +55.9 +13.6 
EDGR crotaice. sche oe sane 2000 +58.5 + 1.6 
Suby: 85 eee dial enn 1500 +11.9 —20.6 
ne eT Se a 1500 + 9.4 —23.7 
and since Pfliiger’s estimates seem to be at least as trustworthy as 
Pettenkofer & Voit’s, and lead to exactly the opposite results, the 
only verdict possible, so far as these experiments are concerned, is 
“Not proven.” 
Later Experiments.—Shortly after the publication of Pfliger’s 
critique, E. Voit,t in a preliminary communication, presented the 
results of investigations upon this question undertaken in the 
Munich laboratory. So far as the writer is aware, no complete 
account of these experiments has yet appeared, but the data given 
by Voit in the preliminary account show a retention in the body 
of 8 to 10 per cent. of the carbon of the metabolized proteids, and 
to this extent confirm the earlier results obtained by his father. 
He believes the observed gain of carbon to be too great to be 
accounted for by the storage of glycogen and interprets it as 
showing a production of fat from proteids. 
* Includes a correction of Pettenkofer & Voit’s figures for the urinary 
nitrogen: Loc. cit. p. 263. 
+ Thier. Chem. Ber., 22, 34. 
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