APIS. 



ferrocyanide or ammonium chloride and only a slight opalescence with 

 three times its volume of absolute alcohol; it slowly gave a slight floccu- 

 lent precipitate with nine times its volume of absolute alcohol. It showed 

 a s'trong digestive action on herring and on hard-boiled white of egg when 

 kept in contact with them for forty-eight hours at about 20°, but had no 

 action if previously neutralized, showing that the enzyme, like pepsin, would 

 only act in acid solution. In order to see if it was identical with pepsin, 

 a 0.5 per cent, solution of the latter in dilute acetic acid was allowed to 

 act on herring and white of egg; this appeared to have a weaker action 

 than the mead-vinegar, and was therefore allowed to act for six days; 

 the liquids obtained in the two cases were then compared. That from the 

 • digestion Contained both albumose and peptone, as was to be expected, 

 but that from the action of the mead-vinegar contained no peptone, but 

 only albumose. and it appears therefore that the enzyme which it contains 

 is not identical with pepsin. It may be the same as the blood-fibrin dis- 

 solving ferment which was extracted by Erlenmeyer and V. Planta from 

 the bodies of bees. W. Lenz (Apoth. Zeit., September 7, 1910, 678). — • 

 Pharmaceutical Journal and Pharmacist, November ip, 1910, p. 609. 



SPECIFIC USES OF APIS. 

 By John Fearn, M. D.: 



Specific Medicine Apis Mellifica is a renal eliminant, and may be used 

 in both retention and suppression of urinp. It is one of the best remedies 

 for rough, red rashes on the skin, that burn and sting, and under favorable 

 conditions eventuate in urticaria and erysipelas, these conditions probably 

 owing their cause to impaired renal elimination. Apis is the remedy in' 

 throat troubles and diphtheria with much inflammation and edema, the soft 

 palate looking like a waterbag, with burning and stinging. The same is 

 true in diseases of women attended by burning and stinging, or in urinary 

 troubles, burning and stinging in bladder and urethra, strangury, a con- 

 stant desire to pass urine, with much pain and straining, but with only a 

 few drops passed at a time, tinged with blood. In dropsies, post-scarlatinal 

 and general, where limbs and abdomen swell and pit on pressure. Apis is 

 valuable. Most troubles that can be relieved by Apis, are made worse by 

 heat, and are relieved by cold applications. 



Indications. — Itching, with burning of any part. 



Use. — In diseases of the skin; when the urine is scanty; in irritation of 

 the bladder or urethra. 



Dose.— Sp. Med. Apis, gtt. v. 

 Water, _^iv. 



Misce. 

 Sig. — A teaspoonful of the dilution every one to four hours. 



Dose: {Felter, American Dispensatory), Sp. Med. Apis, i-io to 

 2 drops. The larger doses in dropsies; the smaller in cutaneous dis-- 

 orders and in vesical irritation. < 



PRICES OF SPECIFIC MEDICINE APIS. 



/4-tt) package soc. each. By njail, $1.02. 



54-lb package $1.50 each. Not mailable. 



l-lb package $3.00 each. Not mailable. 



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