44 Veterinary Medicine. 



Hog Cholera. McFadyean's. Swine Plague. 



Hen orpigeon has slough Hen or pigeon dies in 48 



where inoculated, diar- hours, after drowsi- 



rhoea.ruffled plumage, uess, drooping wings, 



somnolence sunken head, ruffled 



plumage, liquid stools, 

 sott, black comb and 

 wattles, prostration _. 



Rabbits getting o icc. Rabbits getting 0.5 to Rabbits getting o.oicc. 

 virulent culture sub- icc. culture subcutem culture subcutem die 

 cutem die in 5 to 7 days had tumor like walnut in 16 to 20 hours, with 



with eularged spleen but recovered inflamed serosse and 



and necrotic liver foci. luiig; Petechise 



Weaker culture kills in Weak cultures kill in 4 



10 to 20 days with en to 10 days, with in- 

 larged spleen, or re flamed serosse and sup 

 covery ensues puration 



Guinea pigs die in 7 to 12 Not pathogenic to Guin- Guineapigs die in i to 4 

 days eapig days 



Swine inoculated subcu- Swine inoculated have 



tem have often local locallesions only, only 



lesions and bacilli, also exceptionally fatal 



in lymph glands, only 

 exceptionally fatal 



Ingestion of virulent cul- Ingestion of 30 cc. by Ingestion of virulent cul- 

 tures by fasting pig pigs proved a 1 w a y s turesbypigs is usually 



causes bowel lesions fatal harmless ^ 



and death 



Intravenous inoculation Intravenous inoculation 



in pig causes septicse- causes septicsemia and 



mic lesions and death, death in i or 2 days., 



or chronic diseases and 

 typical bowel ulcers.. 



Intrapulmonary infec- 

 tion causes pleuro- 

 pneumonia '. 



Swine erysipelas kills inoculated pigeon in 3 to 8 days, and rBbbit in 4 to 8 



days. 



Invisible, Infinitesimal Hog Cholera Microbe. 



The later research of Dorset, Bolton and McBryde, of the Bu- 

 reau of Animal Industry, shows clearly that the Bacillus Pestes 

 Suis (B. Suisepticus) and the B. Choleras Suis do not exhaust 

 the list of pathogenic microbes in the familiar swine fevers. An 

 infinitesimal microbe which passes readily through the Chamber- 

 land and Berkefield filters, and the existence of which has not 

 been demonstrated by staining and microscope, produces symp- 

 toms and lesions as characteristic as those due to the pure cul- 

 tures of the hog cholera bacillus and is incomparably more infect- 

 ing. It is also much more deadly, but the few animals that 

 recover from the disease show an immunity as strong as that which 

 follows an attack of the disease caught by simple exposure. 



