1 8 Veterinary Medicine. 



hyperthermia without marked remissions, weak, rapid pulse, hurried 

 breathing, anorexia, emesis, yellow mucosse, nervous disorder — dulness, 

 apathy, stupor, paraplegia. Value of precursory conditions. Prognosis 

 grave. Prevention, Treatment: remove source of poison, antiseptics, drain- 

 age, internal antisepsis, strychnia, quinine, iron chloride, stimulants, sup- 

 porting, easily digestible food, sponging. 



At first introduced to indicate the supposed results of pus and 

 septic material respectively in the blood, these terms have come 

 to represent the clinical phenomena which come from the intro- 

 duction into a susceptible system of pyogenic and necrogenic 

 microbes and their toxic products. Gradually different affections, 

 which would have been included under the same general terms, 

 came to be identified under specific names, and a number of these 

 will be described as individual diseases — strangles, mouse and 

 rabbit septicsetriias, metritis, phlebitis, omphalitis, rouget, bar- 

 bone, chicken cholera, septicaemia hsemorrhagica, etc. — yet a 

 certain number have been left to be referred to under the generic 

 terms, though respectively due to different microbes. 



Distinctions between Pymmia and Septiccemia. Pycemia is a 

 morbid condition characterized by the formation in different 

 organs of multiple metastatic abscesses, dependent on the trans- 

 ference, in the blood stream, of infected clots, or particles con- 

 taining pus microbes, and their arrest at distant points, so as to 

 cause foci of suppuration commencing with the intima of the 

 vessels. 



Septiccemia indicates a general infection often by the same mi- 

 crobes, but showing its results in enlargement and blood engorge- 

 ment of the spleen and lymph glands and necrotic foci of the 

 liver, kidneys and othgr organs, but without the formation of 

 multiple abscesses. The presence of the microbes in the different 

 organs affected, shows that it is not due to the diffusion of the 

 toxic chemical products alone, as at one time supposed, and the 

 lack of abscesses appears to be due to the absence of clots or of 

 modified and adhesive leucocytes or hsematoblasts, which ad- 

 hering to the epithelium of the vessels predispose to suppuration. 



The two conditions are, however, often combined, constituting 

 what is known as septico-pycemia. 



As in the occurrence of other infecting diseases, the condition 

 of varying susceptibility must be taken into account, one indi- 

 vidual, or one species resisting an inoculation which would be 

 deadly to another. 



