82 Veterinary Medicine. 



more quickly from artificial pure cultures than from the casual 

 disease. 



Susceptible Animals. Cultures have been successfully inoculated 

 on ox, horse, sheep, guinea pig, rabbit and white mouse. It oc- 

 curs casually in horse and sheep. 



Symptoms. Intestinal Form. The young cattle (i to 2 years) 

 show slight diarrhcea for a time, with soiling of the hips, tail 

 and hocks, before there is any loss of condition, appetite or gen- 

 eral health. For some days the stools become increasingly fre- 

 quent, and fluid, dark green and foetid, and then the abdomen is 

 tucked up, the back arched, the movements weak and tardy and 

 the spirits depressed. There are now observed advancing ema- 

 ciation, ' pallid mucosae, sunken eyes, and there may even be 

 dropsy between the maxillae. The victim leaves its fellows and 

 is found apart lying with the head bent on the neck, the hair 

 erect, and the skin scurfy and hidebound. The diarrhoea, which 

 tends to constant encrease, and may show intermissions, becomes 

 frothy but rarely bloody. 



A measure of appetite is retained but emaciation, anaemia, de- 

 bility and exhaustion advance with great rapidity and the animal 

 dies in three or four weeks in a state of marasmus. When inter- 

 missions are prolonged death may be deferred for months. 



Symptoms. Wasting Form. This may begin like the intesti- 

 nal form, followed by a marked subsidence of the local digestive 

 troubles. The appetite, though not lost nor even diminished, is 

 depraved, the victim chewing bones and other objects ; the skin 

 becomes dry, scurfy and hidebound, the hair stands erect, the 

 back is arched and the belly tucked up, emaciation steadily en- 

 creases becoming extreme, the animal is weak and spiritless, and 

 the eyes are sunken and pale. The breathing is short and accel- 

 erated, and the pulse rapid small and weak, even imperceptible. 

 When lassoed the animal resists feebly and its bellow is low and 

 weak. Infective arthritis is common, rendering the animal quite 

 helpless. The progress may be a gradually advancing anaemia and 

 debility to an early death, but the majority show a favorable ar- 

 rest, so that they may even breed and rear calves before the fatal 

 result follows. A gradual wasting extending over years is a 

 main feature. 



Lesions. Intestinal Form. These are mainly shown in the 



