ii8 Veterinary Medicine. 



Incubation. In inoculated cases this lasts from three to five 

 days, in those due to simple exposure it may appear to extend 

 over eight days. 



General Symptoms. In nearly all cases alike there is a marked 

 constitutional disturbance, the temperature often rising at once to 

 104° to 106° F., and oscillating on successive days between this 

 and 102° ; the pulse is usually normal at first and the breathing 

 is either slightly accelerated or may be made so under slight exer- 

 tion. There is more or less dulness, or at least a lack of the 

 vivacity of youth, the head is somewhat pendent, the eyes maybe 

 semiclosed, the patient may be tardy or even stiff in his move- 

 ments and the appetite may be diminished or capricious, oats 

 being rejected by some and hay or grass by others. The bowels 

 are somewhat confined, the stools consisting of a few small, hard 

 balls covered with mucus. 



Specific Symptoms in the Mild Form. In the vast majority of 

 cases the local symptoms are concentrated on the mucosae of nose 

 and mouth, and the submaxillary lymph glands. Along with 

 the general febrile phenomena, there appear redness and often 

 mottled congestion of the nasal mucosa, which not infrequently 

 extends to the mouth and eyes, as well. Heat of the mouth, the 

 collection of a more or less tenacious mucus, and even uneasy 

 movements of the jaw may be seen. The nasal mucosa, at first 

 dry, is soon the seat of a watery exudation, passing into a cloudy 

 sticky material, and finally a thick, opaque, mucopurulent flow. 

 This may become colored in a variety of tints, dirty white from 

 inhaled dust, brownish or yellowish from exuded blood, or green- 

 ish from food materials. The discharge is usually profuse in the 

 young and may be scanty in the old. Most commonly it flows 

 from both nostrils alike, though exceptionally it is unilateral. 

 In this it differs from glanders which is more often unilateral 

 though at times bilateral. Small abrasions and sores may appear 

 in connection with the softening and shedding of the epithelium, 

 but these are not ragged, irregular and spreading as in glanders. 

 Sneezing or snorting is an inevitable symptom. Epiphora is usu- 

 ally present. Exudations into the nasal sinuses are to be recog- 

 nized by heat of the forehead and flat sound on percussion. 



Very early in the attack a swelling is noticed in the inter- 

 maxillary space, which may be at first confined to the nodules of 

 the lymph glands, thus forming distinct, rounded, hard swellings, 



