i62 Veterinary Medicine. 



This may go on to coma, there may be more or less complete 

 anorexia, muscular trembling, paresis, especially of the hind 

 limbs, or delirious manifestations indicating meningitis. 



Rheumatoid attacks of the muscles and joints usually appear in 

 the advanced stages of the disease, but may appear earlier. They 

 may occur in any latitude but seem to be especially common in 

 cold, damp, inclement northern regions, and at seasons when 

 climatic vicissitudes are sudden and extreme. These may appear 

 suddenly and disappear with equal rapidity, or they may last for a 

 time during and even after an apparent recovery in other respects. 

 When the joints are involved they usually become engorged with 

 exudates in the synovial membranes. 



Lameness in either /ore or hind limb may assume an intermit- 

 tent type developed by exercise and subsiding with rest, evidently 

 bespeaking local arterial embolism, and in such cases it is likely 

 to persist for months. 



A tendency to transudations and dropsical effusions is common 

 in severe cases, showing especially in the filling of the legs, but 

 in certain epizootics, these become strikingly prevalent and have 

 secured for such a special name (^epizootic cellulitis) . Apart from 

 the limbs these affect particularly the inferior surface of the chest 

 and abdomen. The swellings are not necessarily hot nor painful 

 nor petechiated as in petechial fever, yet they may merge into 

 that affection or they may become phlegmonous and develop 

 abscess. 



Complications of many kinds are to be looked for, pregnant 

 mares may abort ; laminitis may set in / the microbes of strangles, 

 contagious pneumonia, cerebrospinal meningitis, septiccemia, 

 pycBmia, etc., may take occasion to attack the debilitated system, 

 and thus complex diseases and manifestations are developed. 



Morbid Anatomy. The lesions may predominate in different 

 organs in different subjects and successive epizootics. It is a 

 protean disease and may expend its main energy on any one of a 

 number of different organs' or systems of organs. 



In the slighter cases the lesions are often largely confined to 

 the anterior part of the respiratory organs. Th.e fauces, pharynx, 

 larynx, guttural pouches ^.ri& nasal mucosa are tumefied, congested, 

 red and covered with mucus, and this condition may extend 

 down to the bronchia. In such cases the blood is normal or may 



