1 86 Veterinary Medicine. 



bronchitis followed, and in others necrotic tracheitis and pulmo- 

 nary gangrene, so that the method has not been widely accepted. 

 If resorted to, the weaker solution is to be preferred, and may be 

 injected through a tracheal ring, or the membrane between two 

 rings twice a day in doses of 3 to 5 centigrammes (45 to 75 drops). 



Injection into the veins of Argentum Colloidale, i per cent solu- 

 tion in doses of ifi oz. (50 to 60 grammes) at intervals of 2 hours 

 has been very strongly advocated by Dieckerhoff who in four suc- 

 cessive cases had complete recoveries in from three to six days. 

 After disinfection of the skin a small trochar and cannula, or a 

 hypodermic needle is introduced into the jugular and the injec- 

 tion made. Ivocal treatment for the swellings was also applied. 



Injection subcutem of the antistreptococcic serum of Marmoreck 

 has been lauded as promptly overcoming the capillary dilatation, 

 and enabling the leucocytes to neutralize the toxins. Extensive 

 experience resulted in many failures, apparently often dependent 

 on the fact that the streptococcus to be antagonized is different 

 from the one used to make the antidotal serum. This introduces 

 an element of great uncertainty in any individual case. The 

 identity of a given streptococcus is not to be determined even by 

 its agglutinins. Besredka thinks it can be by the action of the 

 immune body (fixator, amboceptor), but even if proved, intelli- 

 gent treatment must be deferred until the laboratory decision 

 can be made, and perhaps even until the immune body can be 

 secured from cultures in an animal body. Until a satisfactory 

 investigation has been made, the anti-streptococcic serum is 

 virtually a step in the dark, which may be a brilliant success, or 

 an equally remarkable failure. 



Finally Menveux recommends an artificial compound as pos- 

 sessing all the good qualities of the antistreptococcic serum. 

 This is composed of sodium chloride 5 grammes, sodium phos- 

 phate I gramme, sodium sulphate 20 centigrammes, sodium car- 

 bonate I gramme, caflein chlorhydrate (o grammes, boiled filter, 

 ed water 100 grammes. Inject daily in three doses 135 grammes. 

 Cheron's serum contains the same agents with )^ grm. carbolic 

 acid added. Mainet advises 200 grms. of salicylic acid solution 

 (1:100) subcutem. 



