262 Veterinary Medicine. 



the bacillus ; and sometimes widespread mortality comes in this 

 way. Meat just killed may be thoroughly disinfected by the 

 secretions of a healthy stomach, yet the bacillus may pass through 

 in an envelope of fat, in an undigested mass, or during a fit of 

 indigestion, and infect the intestines. The spores are proof 

 against the gastric juice, and as they are produced in a few 

 hours after death the meat of an anthrax animal must always be 

 considered as exceedingly dangerous. 



Man is much less susceptible than some animals and the 

 disease, wherever inoculated tends to remain for a time lo- 

 calized, as in the skin, lungs or bowels. The forms of the 

 disorder are malignant carbuncle (pustule), malignant (anthrax) 

 cedema, intestinal anthrax and pulmonary anthrax. 



Lesions. The morbid histology is in the main the same as 

 described in animals. In the protracted cases theire is the same 

 dark nonserated blood, forming a loose coagulum, the crenated 

 or distorted blood globules aggregated in irregular masses, the 

 escape and solution of the haemoglobin so as to stain the white 

 tissues, the enlargement of the spleen which is gorged with dark 

 blood, and the hyperaemia of the liver and lymph glands. There 

 is in the affected tissues and usually in the blood, the character- 

 istic large bacillus anthracis. 



In the malignant carbuncle (vesicle) there is first a minute, 

 firm central dark nodule like an insect bite with a lighter colored 

 areole, and showing not only hyperaemia, but blocking of the 

 capillaries, and minute areas of extravasation. Somewhat later 

 the dark centre is surmounted by a small vesicle, beneath which 

 the tissues are becoming necrotic, and the area of congestion and 

 extravasation has extended and thus the local disease advances 

 by a constant invasion of new tissue which in its turn becomes 

 the seat of coagulation necrosis. On microscopic section the 

 central necrotic part shows the cells of the rete Malpighi separated 

 by a finely granular coagulum, and the papillae are greatly 

 swollen by serous and haemorrhagic exudate. The cell nuclei 

 are necrotic and no longer take a stain. The capillaries are 

 gorged with red globules and bacilli. In the surrounding tissues 

 there is much congestion and exudation, with [numerous points 

 of extravasation, but the abundant multinuclear cells retain 

 their staining power. 



In Anthrax CEdema which appears in parts like the eyelids, 



