Anthrax in Man. 263 



neck and forearm where there is an abundance of loose connective 

 tissues and a scanty blood supply, there is no hard central nodule, 

 but a diffuse soft infiltration, with points or patches of a yellow 

 or reddish color. The capillaries are congested with minute 

 emboli and extravasation and there is an excessive and rapidly 

 spreading exudation. It shows a great tendency to early gen- 

 eral infection and may end in vesication and local gangrene or in 

 favorable cases in resolution. 



In Intestinal Anthrax (intestinal mycosis) the lesions are 

 usually concentrated on the small intestines, while the stomach 

 and large intestines in the main escape. The walls of the bowel 

 are of a dark red, and greatly thickened by exudation and ex- 

 travasation, which also mixes with the ingesta giving it a dark 

 bloody tinge. At intervals on the mucosa are nodular hsemor- 

 rhagic swellings from the size of a linseed to a pea, with com- 

 mencing necrotic changes or the formation of sores. The mesenter- 

 ic glands are swollen, infiltrated and hsemorrhagic and like the 

 other lesions abound in bacilli. H5rpersemia and engorgement 

 of the Uver and above all of the spleen are the rule. 



In Pulmonary Anthrax (wool sorter's disease) a sanguineous 

 liquid is found in the lower trachea and bronchia, and not in- 

 frequently in the pleurae and pericardium. The bronchial glands 

 are swollen, hypersemic and often hsemorrhagic, and exudations 

 and extravasations may be found in the mediastinum and lungs. 

 Lesions of the intestines and spleen are common, and in all alike 

 the bacilli are found. 



In certain cases the anthrax lesions are found in the brain, or 

 any part of the body, but in all they show the same general 

 characters and the same specific microbe. 



SYMPTOMS : DIAGNOSIS. 



Malignant Vesicle (pustule). Symptoms vary somewhat but 

 are in the main as follows : An itching papule appears in the 

 seat of inoculation, which might be mistaken for an insect bite, 

 but for the dark red color of the centre. Occurring on an un- 

 covered portion of the skin, in an anthrax district or near a 

 factory where anthrax products are likely to be used, this should 

 at once create suspicion. Soon the dark centre is covered by a 

 small vesicle, with clear contents which later become bloody. 



