Anthrax in Man. 267 



same agents, with phenic acid (5 or 10:100), or with pyoktanin 

 (1:1000) will prove useful, and as in the malignant pustule the 

 surface should be kept disinfected by a compress wet in solution 

 of the mercuric chloride or biniodide, carbolic acid, iodized phe- 

 nol, formalin or pyoktanin. If the pain of these applications is 

 very acute cocaine will be demanded or even ether. If ether is ap- 

 plied to the surface its evaporation will cool the parts and retard 

 the proliferation of the bacillus. Under other conditions cold 

 water, pounded ice or snow may be applied. 



Treatment of Intestinal Anthrax. When anthrax flesh has 

 been eaten, or when there are symptoms of incipient intestinal 

 anthrax, the first resort is an emetic of ipecacuau, followed by an 

 active oleaginous purgative to clear the prima via of bacilli and 

 their toxins. To these may be added potassium iodide, pyok- 

 tanin, sodium salicylate, quinine or tincture of muriate of iron, by 

 way of keeping in check the multiplication of bacilli. To coun- 

 teract depression and heart failure digitalis, strophanthus or 

 strychnia with alcoholic stimulants may be resorted to. 



In Pulmonary Anthrax the same principles are applicable. 

 The patient may be made to cautiously itfhale gaseous chlorine,, 

 iodine or bromine or a solution of iodide of potassium in an atom- 

 ized condition. The vapor of carbolic acid, eucalyptol, or oil of 

 cinnamon may be tried. 



The irritable stomach may be soothed by oxide of bismuth, 

 with milk, beef tea and other bland nutritive or stimulating 

 draughts. 



The grave character of internal anthrax, however, is such that 

 resort may be had to one of the various anti-toxins, antidotal 

 cultures, serums, and immunizing agents that have proved useful 

 in different hands. Unfortunately such agents do not seem to act 

 in the same manner on all genera, and what has been effective in 

 one of the lower animals may fail in the human being. Thus 

 Roger found that sterilized cultures of bacillus prodigiosus re- 

 tarded or obviated anthrax in rabbits, but hastened its progress 

 in the Guinea pig. 



The sterilized cultures of the pneumococcus of Friedlander 

 (Buchner) or of the staphylococcus pyogenus aureus, (Paw- 

 lowsky) when injected subcutem have proved antidotal to an- 

 thrax. Emmerich has successfully used erysipelas serum sub- 

 cutem in the treatment of anthrax. (Miinch. Med. Woch. 



