278 Veterinary Medicine. 



symptom may be the swelling of a joint with more or less en- 

 gorgement of the limb from attendant lymphangitis. There 

 can usually be detected around the margins of such swellings firm, 

 tender cords, representing the larger lymphatic vessels and often 

 branching in their course. In the absence of the engorgement, or 

 when it is slight, these cords may be the main evidence of the 

 disorder, and in the hind limb usually follow the course of the 

 flexor tendons on the inner side of the digit, metacarpus and 

 thigh. At intervals along the line of the cords appear nodular 

 masses (farcy buds) varying in size from a pea to a hen's egg, 

 and showing a great disposition to soften and discharge a glairy, 

 sanious or more or less bloody liquid. The inner sides of the 

 fetlock and tarsus are favorite seats of these nodules but they 

 may form at any point. On the trunk also the corded lympha- 

 tics and nodules follow the lines of the veins and lymphatics, and 

 here there may be the complication of large intermuscular 

 abscesses often in connection with the groups of lymphatic 

 glands. 



Latent or occult glanders is often met with, the indolent, specific 

 lesions being confined to some internal organs, like the larynx, 

 lungs or womb, or to the testicles, the nasal diagnostic symptoms 

 being absent. A chronic cough, with a slight purulent discharge 

 from the nose, a chronic leucorrhoea, a swollen testicle, or simply 

 a persistent low condition or weakness without apparent cause, 

 may be the only indications, and special means of diagnosis are 

 demanded. 



Special Means of Diagnosis. In occult cases, the disease may 

 be identified by inoculation, or by the mallein or agglutination test. 



Inoculation is best performed on a very susceptible animal. If 

 the suspected discharge from the nose, vagina, open sore or pre- 

 ferably from a freshly incised nodule is inoculated subcutem in 

 the flank of a male Guinea pig, or better in the peritoneum, there 

 develops a local ulcerous sore and on the second and third day a 

 violent orchitis in which pure cultures of the bacillus can be ob- 

 tained. The caseous and purulent centres are found not only in 

 the testicle but along the line of the spermatic cord, affecting the 

 tunica vaginalis and connective tissue. Death usually follows in 

 four to fifteen days. The cat and dog can also be utilized, inocu- 

 lation being made on the forehead. Old wornout, but otherwise 

 healthy asses, and even horses make very available subjects, in- 

 oculation in the nose speedily developing acute glanders. In 



