526. Veterinary Medicine. 



resulting , in some instances from the use of cow's n;iilk cannot 

 well be. charged with, a marked enerease.of casep in which the 

 mesenteric tubercles ppint so directly to infection thrgugli the 

 food. If it ,is ,held that the. tubercle bacilli in the .milk.are harm- 

 less, we wait for eviienc^.pf the rpal pause, of such en,crease and 

 lopalization,. ■.....; , . , ,, , .,._ ,,,, ., ..:,;.-,,. 



The experipjpnts.of Adami show, that tube;rcle js directly. trans- 

 missible from man -to ox_t.hpugh usually with decreased vji^nlence. 

 More, recently, R,aveneLusing.the,bacillus,deri\r^d, from, the mesen- 

 teric s glands of a cjijld, injected intravenously two . tuberculin- 

 tested .cal.ves,. with. 5 cc, each of the culture, producing exalted 

 hyperthermia, miliary tuberculosis of the lungs, tuberci^lpsis and 

 caseation of the bronchial and. mediastinal glands, and d,eath in 

 17 days. - , , , • ,•..-,.., 



As showing accommodation to. environment, Bataillpn and 

 Ferre found that the. bacillus (mammalian and, avian) grown in 

 frogSj Dubard that grown in fishes, Krahl that grown, in, frogs, 

 snakes, fishes and lizards, and Miieller that grown in the glpw 

 worm, thereafter grew at summer temperature (68° E.) and grew 

 poorly or not at all in the bpdies of mammalia. ^ 



The tubercle bacillus is primarily and essentially one,.b.ut this 

 must not close our eyes to the fact that in different hosts- and 

 environments it takes on very different habits; so that for the 

 time and in these surroundings, it is materially modifi.ed in its 

 pathogenic attitude toward different races. Yet its ready vari- 

 ability when conditions are favorable to change, renders it desir- 

 able to destroy it in all its forms, and especially in those which 

 approximate most closely to those that prey on man and animals. 



An impartial review of the, whole field warrants the conclusion 

 that the nineteen young (and therefore .comparatively unsuscep- 

 tible) cattle which in Koch's hands failedto develop generalized 

 tuberculosis after inoculation with the virulent sputum of r»an, 

 and the smaller numbers that resulted in the same way under 

 similar treatment in the hands of Th. Smith, Dinwiddle and 

 Adami, while showing a very marked limitation in the suscepti- 

 bility of the sound bovine system to \yeak bacilli frpm man, can- 

 not disprove the many well authenticated cases of the transmis- 

 sion of tuberculosis, irom cow to man and the reyerse. The 

 greater potency of the bovine bacillus over that of man, in its 



