^66 Veterinary Medicine. 



easily detached, the epithelium of the glomeruli and convoluted 

 tubes swollen and their nuclei multiplied. A gelatinoid exudate 

 is usually present in the renal pelvis. Congestions have been 

 found in the right gastric cul-de-sac and less frequently in the in- 

 testines. Exudations have also been found in the cerebro-spinal 

 nervous system, the laryngeal mucosa and the conjunctiva. The 

 latter is usually cyanosed. 



Prevention. The first consideration is to keep work horses in- 

 doors or in a kraal during the summer or sickly season. Here 

 they must be fed on dry hay and grain only, grass being strictly 

 withheld. If it becomes absolutely necessary to feed green fodder 

 of any kind it should not be cut until all dew or rain has com- 

 pletely dried off in the heat of the sun, and if kept over night 

 should be kept under cover and again dried before feeding. 

 When taken out to work the animal should wear a check rein or 

 muzzle so that he cannot by any chance reach the green vegetation. 

 This rule must be most strictly adhered to at night or during 

 damp weather. 



For horses turned to pasture a fair amount of protection may 

 be secured by shutting them in a stable or kraal before sundown, 

 and until the vegetation has been thoroughly dried by the sun 

 the next morning. 



Immunization. A horse that has recovered from the sickness 

 has been long held to be immune and will bring from six to ten 

 times its former price. As any disease is liable to be called the 

 sickness, this enhanced value is too often insubstantial. Wilt- 

 shire even says that all ,' ' salted ' ' horses eventually die of horse 

 sickness if allowed to live long enough. Be this as it may Eding- 

 ton appears to have established a reasonable measure of immunity 

 by his protective inoculations. He takes a recovered ( ' salted ' ) 

 animal and reinoculates it at intervals with encreased doses of 

 virulent blood. After the last of these inoculations the subject is 

 allowed to rest for a long period of time, and is then reinoculated 

 with a small- dose of virulent blood. A definite amount of this 

 horse's virulent blood is mixed with 50 cc. of serum and injected 

 subcutaneously ; some days later 30 cc. of the same serum with 

 the same dose of blood is injected ; at a later date the procedure is 

 repeated, with a reduced dose of serum, and fourteen days later 

 pure virulent blood is injected." The result was satisfactory. 



