Dourine. 579 



liypopion, cataract, nasal discharges, facial periostitis, dyspnoea 

 and syncope. 



Symptoms in Rabbits. Rouget found in inoculated rabbits, 

 extensive gangrene of the skin, involving even the cranial bones, 

 ulcerative keratitis, hypopion, panophthalmia, following on the 

 earlier genital troubles of vaginitis, swelling and discharge. 



Treatment. Some cases recover spontaneously a few may be 

 aborted in the earliest stage of the disease, but cases that have 

 advanced to any extent and assumed a grave character are prac- 

 tically hopeless. 



An important element in treatment is to do away as far as pos- 

 sible with the cause of generative excitement since the disease 

 is aggravated and more rapidly advanced by frequent copulation. 

 Rodloff from a very wide experience speaks highly of castration 

 of the stallion. Castration of the mare has not been specially 

 advocated and the absence of marked lesions in the ovaries, may 

 deter the veterinarian, yet whatever promises to lessen in any de- 

 gree the genesic excitement is not to be despised, and the measure 

 has besides a sanitary value for other animals. 



Early local treatment is the most promising, and especially if 

 it can be applied to exposed animals during apparent incubation. 

 Inject the urethra, sheath, vulva, vagina and uterus with 

 antiseptic lotions, and apply them to the external sores. Mercuric 

 chloride 1:2000, carbolic acid 2:100, silver nitrate 1:250, calcium 

 chloride i : 1 00, or chlorine water may be taken as examples. When 

 local swellings have supervened it would be entirely appropriate to 

 incise them freely or even to excise them and cauterize thoroughly 

 with stronger agents. 



Internal treatment by mercuric chloride i}4 to 2 grains, potas- 

 sium iodide 2 to 5 drs., arsenic 7 to 14 grains, has been widely 

 used but to little purpose. The same may be said of Rodloff' s 

 treatment by tonics and carminatives (sal ammoniac, camphor, 

 iron, angelica, gentian, ginger and valerian). 



Prevention. The one thing to be secured is the prevention of 

 copulation with any animal that has been affected, or exposed to 

 this disease in the past three years. 



I St. Any stallion or mare once affected must be excluded from 

 breeding for at least three years after apparent recovery. 



2d. Every such animal that has been expo.sed by copulation 



