African Coast Piroplasmo sis of Cattle. 619 



is a sudden extreme elevation of temperature (106° F. ) with at 

 first little change in appetite, rumination, breathing or secre- 

 tions. Slight salivation, glazing of the faeces, dulness,pain and 

 stupor come on by degrees. Resting of the chin on the manger, 

 or, during the prolonged recumbency, on the ground, glazing 

 of the eye, weakness and staggering, intermaxillary oedema, 

 foetid, even bloody, diarrhoea, cough, dyspncjea, flatness on 

 percussion over the lungs, with abnormal murmurs, and at times 

 crepitating subcutaneous swellings are to be noted. 



Lesions. Swelling and hsemorrhagic condition of the lymph 

 glands is a prominent lesion. Congestion of tonsils, larynx and 

 trachea ; oedema of the lungs, pleural liquid effusion ; conges- 

 tion and ulceration of the abomasum, with dropsical condition of 

 the folds ; congestion hsemorrhagic effusion and even necrotic 

 changes of the intestinal mucosa, especially of the caecum, colon 

 and rectum ; infarcts of the kidneys ; and extensive ecchymosis. 

 Unlike Texas fever the spleen is comparatively normal and there 

 is no dearth of erythrocytes. 



Prevention. As treatment is as fruitless as in Texas fever 

 attention has been mainly directed to prophylaxis. I^och ad- 

 vises immunization by the subcutaneous injection of 5 cc. 

 defibrinated blood, from the jugular of a recovered ox, to be re- 

 peated every two weeks for five months. His previous inocula- 

 tions of 5 cc. and 10 cc, extended over five months, failed in the 

 hands of other veterinarians, including those working under his 

 own direction and failed to secure the confidence of the stock- 

 owners. It is claimed that the inoculation is harmless, and can- 

 not contribute to extend the infection, and yet we are told that 

 the inoculated animal continues to bear the live ring-like para- 

 sites in its blood, and becomes susceptible. 



