PRACTICAL RESULTS— DESENSITISATION 603 



intravenously or intrathecally. The doses mentioned are most 

 suitably given by the gravitation method. If any anaphylactic 

 symptoms appear, the administration must be temporarily stopped 

 and then cautiously resumed. The chief symptoms are dyspnoea, 

 with pallor or cyanosis, fall in the blood pressure, with feeble 

 pulse, asthmatic symptoms, with cough, and sometimes vomiting. 

 Adrenalin and atropine are the most efficient drugs. In all 

 cases the administration of serum by the methods mentioned 

 should be carried out slowly and with caution. Anaphylaxis is 

 sometimes a real danger, but the risks, when we take into 

 account the necessity for the prompt treatment of tetanus, have 

 been exaggerated. We may add that the repeated subcutaneous 

 injections for preventive purposes of the usual quantity of 3 c.c. 

 of serum are unattended by any danger. It may also be stated 

 that in relation to anaphylaxis it is only the amount of serum 

 which matters — the antitoxic value is not a factor. 



