DRUGS ACTING ON THE NERVOUS SYSTEM 



(A) Drugs stimulating the motor cells of the inferior cornua. 

 Strychnine Ammonia Opium ■» 



Brucine Anesthetics Ergot I Primary action 



Thebaine J 



Uses. — Strychnine is employed in paraplegia resulting from diseases 

 of the spinal cord after irritation caused by the lesion has passed away. 



(B) Drugs depressing the motor cells of the inferior cornua. 



Physostigmine 



Bromides 



Ergot 



Nitrites 



Gelsemium 



Emetine 



Turpentine 



Salts J Magnesium 



Alcohol 



Ether 



Chloroform 



Camphor 



Carbolic Acid 



Nicotine 



Veratrine 



Mercury 



Arsenic 



Potassium 



Lithium 

 Salts < Antimony 



Zinc 



Silver 

 Saponin 

 Chloral 

 Morphine 

 Sodium Apomorphine 



Uses. — Drugs depressing the motor cells of the cord are serviceable 

 as antidotes in the treatment of poisoning by those exciting the same 

 (chloral and bromides in strychnine poisoning), and in convulsive and 

 spasmodic disorders, as chorea and tetanus. 



III. — Drugs Acting on the Nerves. 



The nerve terminations, rather than their trunks, are influenced by 

 drugs. 



(A) Drugs influencing peripheral sensory nefve-endings. 



( 1 ) Stimulating sensory nerve-terminations. — Counter-irritants. 

 (See p. 52.) 



General Uses. — They are applied externally (mustard and heat) to 

 stimulate the heart and respiration in heart failure, shock and collapse. 



(2) Depressing sensory nerve-terminations. — These include local 

 .sedatives or anodynes, which lessen sensation ; and local anesthetics, which 



abolish sensation. 



LOCAL ANODYNES. 



Aconite Morphine Veratrine 



Menthol Chloral Heat 



Carbolic acid Prussic acid Cold 



Atropine Sodium bicarbonate 



Cocaine 

 Eucaine 



LOCAL ANESTHETICS. 



Stovaine Holocaine 



Novocaine Cold 



spray 



Ether 

 Methyl-chloride 



Uses. — The local anodynes are employed to relieve pain of an inflam- 

 matory, rheumatic or neuralgic character, and itching. The local anes- 

 thetics are employ el to prevent pain in surgical operations. 



(B) Drugs influencing peripheral motor nerve-endings. 



(1) STIMULATING MOTOR NEHVE-TERMINATIONS. 



Strychnine Aconite Pyridine 



Pilocarpine Nicotine 



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